GENETICS
by Franck BOUTINET and Rodolphe PERROT
BASIC GENETICS
DNA
What is DNA ?
Structure of DNA (make a link with corresponding word and concepts - use animations !)
DNA moving in 3D - DNA Web Page
How to extract DNA from any living thing
DNA Extraction: intermediate level
DNA Replication Enzymes
DNA Opening with DNA helicase
DNA Cap in 3D
The Invention of the Genetic Code - (make a link with corresponding concept and word)
The genetic code (to associate with word(s))
The code for various organisms
The mitochondrial genetic codeDNA IN OUR CELLS
A Virtual Cell!
Mitosis pictures in 3D
Mitosis animation (idem)
Mitosis animation 2
Meiosis animation (idem)
Meiosis animation 2AND IN PLANTS
Introduction
Analysis of Genomes by Reassociation Experiments
Repeated Sequences
Organization of Single-copy Sequences
Evolution of Repeated Sequences in Cereals
Estimating the Number of Expressed Genes
Structure of Chloroplast
Chloroplast Genome Organization
Structure of chloroplast DNA isolated from rice
mtDNA (Mitochondria DNA)
(take different links, use pictures… - good site to explain what is mtDNA!)
Structure of Mitochondria
Mitochondrial Genome Organization
Plant Molecular Genetics
RNA editing in plant mitochondria, cytoplasmic male sterility and plant breeding.
(we find mitochondria in the human cells like plant cells!)DNA TO CHROMOSOME, GENE CONCEPT
Introduction to Chromosomes
What can our chromosomes tell us?
What is inheritance?
What is a gene?
A look at transcription and translationBOOKS
Recombinant DNA Technology
Chromosome DNA and Its Packaging
DNA-binding Motifs in Gene Regulatory Proteins
Basic Genetic Mechanisms
Basic Genetic Mechanisms (follow)GLOSSARY AND EXERCISES
lesson : Mendelian genetics
lesson : Genetic Diseases
lesson : Nucleic Acids and Protein Synthesis
lesson : Cell Growth and Division
lesson : Meiosis
lesson : DNA, RNA, Protein Synthesis
Glossary
quiz 1
quiz 2 : Genetic Engineering
quiz 3 : Power Quiz: Genetic Abnormalities
quiz 4 : genetic mapping
quiz 5 : genetic pop'
quiz 6 : Human Genetic Disease and Cancer Quiz
quiz 7 : free genetic test
exercises in molecular biology
quiz 8 : Cellular Genetics (Cytogenetics)
quiz 9 : transfer of DNA
exercise : 5 problems
Recombinant DNA Technology Problem Set
quiz 10 : Bacterial Genetics/Recombinant DNACOMMUNICATION
mailing-lists (choice)
mailing-list of Hum-Molgen
discussion forum of Hum-Molgen
Free Chatroom (idem)HUMAN GENOME SEQUENCING MAPPING
(Medline) mapping
mapping (take each link - chromosome 1 to Y)
marker mapping (take each link - chromosome 1 to Y)
Human Telomere Atlas
Technical
videos with RealAudio PlayerDATABASES
Database
Database
A human mitochondrial genome database
Swissprot
Infobiogen : sequence analysis (only in French! good website!)
The Genome Data Base - GDB
Search in GENE, MARKER, PHENOTYPE DATABASEHOW TO CONQUER A GENETIC DISEASE ?
GENETIC DISEASES
Genetic diseases (Génétique humaine)
Genetic diseases (The following is an alphabetical list of various genetic diseases - pictures)
Introduction
What gene is at fault ?
What protein does it make ?
Can the protein or gene be replaced ?
Mitochondria Genetic and Disease (video)
promise of genetic engineering and testing… (video)
Genetic link to cancer (video)GENE THERAPY
(introduction : what is the gene therapy)
The Delivery Group ; Gene Therapy/Disease Targets
The Delivery Group ; Gene Therapy/Viral Vectors & Non-Viral Vectors :
how to transfer the gene to the hill target cell ?
The Delivery Group ; Polymer Vectors
The Delivery Group ; Gene Therapy/Chimical Trials
The Delivery Group ; Gene Therapy/Commercial Potential :
the most important developments in medicine
(news on gene therapy)
(Cell and Gene Therapy)
(Goldyne Savad Institute of Gene Therapy at Hadassah)
Genetic Medicine (video with Real Player)NEWS
Search 'genetic' on CNN website
(Video)
The race to map genetic material… (video)
Half the patients had a known genetic risk for alzheimer's.
Companies involved in genetic research…(video)
The United States and Britain agreed to share (video)
Radioactivity and the risks of cancer or genetic effects (video)
Monsanto used private investigators to check on farmer (audio)
News
Genome Meetings, Courses, Conferences, and Workshops
Current Events in GeneticsNewspaper (The American Journal of Human Genetics)
Newspaper (Human Molecular Genetics)
Newspaper (Gene Therapy)
Newspaper (Human Gene Therapy)
Newspaper (The Journal of Gene Medicine Website)INSTITUTIONS
Le Généthon
AFM : French association
National Institute of Health
The National Human Genome Research Institute
National Center for Genome Resource
The Institute for Human Gene Therapy
The Sanger Centre
Monsanto CompanyOTHERS
(human genetics)
(Blazing a genetic trial)
http://www.cancergenetics.org/ (Genetic of cancer)
(interesting address)
(The Gene Delivery Group Web Site)
(University of Minnesota Gene Therapy Program)
(Religious Tolerance.org (Human Cloning)
(Human Genome Project)
(Human Genome Diversity Project by Morrison Institute - FAQ)
(CHLC Genetic Mapping)
(Gene Therapy News - Related Papers from Eubios Ethics Institute Publications)
(GeneCards : human genes, proteins and diseases)
(Article - Molecular Genetics of Alzheimer's disease
With special emphasis on presenilin, amyloid beta precursor protein and apolipoprotein E genes)
(Article - Plant genome Analysis)
(Database - The DEAMBULUM)
infobiogen
(The dictionary of cell and molecular biology - Britannica, 3rd edition)
(Down Syndrome - Understanding the gift of life)
(DNA from the beginning)
(Welcome to the Mendel Web)
(A Sample Genetic Algorithm Applet)
GMO'S (food - by BBC News)GENETICS IN OUR SOCIETY
CLONING
Introduction : Human Embryo Cloning
Why Clone Human Embryos ?
Human Genome Project
Human Cloning Plans (listen with RealAudio)
Reengineering the Species (human)
Federal Guidelines for Human Embryo Cloning
Background information
Can we and should we clone humans ?
executive summary
Human Cloning Techniques
How to Clone a Human ?
Conclusion : Lets Wrap it Up !
FAQ
Ethics
Ethics
Ethics (gene therapy)GMO'S
Genetically Modified Plants… Preface
Introduction
Progress on our plates (use the different links ! particularly 'section II')
FAQ : GMO's
Chemicals and GMO's
Operation Terminator
What is a GM food ?
Killer CornILLUSTRATIONS
first picture on the left (for CLONING)
first picture on the left (for CLONING)
first picture on the left (for CLONING)
animatedgif (for CLONING)
on the left
possibility of background
possibility of background
picture : DNA structure
A brief key to basic genetics
In every page of this site you can take pictures to illustrate.
to insert counter in our website (thank you !)
Audio clip - to insert with word(s) corresponding - Interviews
Chromosomes
Nucleotides and nucleosides in 3D
More nucleotides in 3D
you can take some different chapter (1 - 32) : make some links,
use the animations and audio/videos to illustrate.
Pictures and concepts
Pictures and concepts 2 (idem)
Webmaster Utilities
Javascript
Olivier ROUDAIRE and Guillaume BOMAL
FORUMS & MAILING LISTS
MORRISON INSTITUTE
Questions and answers about the human genom diversity project: Goals and methods
International communication forum in human genetics
General site containing a lot of links to forums and discussion groups (human genetics), also contain e-mail of specialists.
SCIENTIFIC AMERICAN
Site dealing with cloning technique, prospects and ethical problems, a forum allow to discuss about this last subject.HYPERTEXTBOOKS
Hypertextbook from the MIT Contains the following chapters: Mendelian Genetics, Prokaryotic Genetics and Gene Expression, Recombinant DNA.
Contains basic to new information, from Mendelian laws to cloning. Explains different techniques and applications of molecular genetic: Hybridization, Cloning...
Every chapter is illustrated by clear schemas and tabs which makes this site most attractive
Hypertextbook from ENCARTA
Mainly contains general, historic and descriptive information concerning genetic and ethical issues, but also contains chapters dealing with techniques such as cloning and sequencing.
Other chapters deal with good and bad applications of genetic technology among which : gene therapy and risks of Biological War and genetic determinism.
Links to others sites (human genom project,hypertextbooks,glossaries...)
Interesting site even if it only contains text.COURSES
Molecular Genetics from the U.S. Department of Energy
Generalist site about human genetics, contains the following chapters :
Mapping and Sequencing the Human Genome
Model Organism Research
Informatics: Data Collection and Interpretation
Impact of the Human Genome Project
Illustrated siteJOURNALS
GENETICS
A periodical record of investigations bearing on heredity and variation
Only abstacts available
American Journal of Medical Genetics
Reports of seminars about human geneticsDICTIONNARIES & GLOSSARIES
A genetics glossary
Dictionnary of genetics terms. Not illustrated
Glossary of genetic terms
Dictionnary of genetics terms with illustrations and links to related terms
Institut Pasteur
Index English-French for genetic terms, provides the translation of genetic engineering
(French site)INSTITUTIONS
THE GENETIC SOCIETY OF AMERICA
Provides links concerning conferences and meetings dealing with Yeast Genetics and Molecular Biology and Drosophila Research
HUMAN GENOME PROJECT
Welcome page all about the human genome sequencing project : ethical legal social issues ,project Information, Medical Applications, Publications and the research in progress..DATABASES
INFOBIOGEN
Generalist database provides tools to analyse gene sequences, compare and simulate the effect of enzymes on them.
FLYBASE drosophila genome database
All you need to know about one of the most studied animals.You can search for gene structure and functions, gene products Also contains images of drosophila, literature references and links to the Drosophila Genome Projects.
Saccharomyces genome database
Contains information concerning molecular biology and genetics of different yeast model organisms:
genes, sequence analysis links to others yeast web sites, literature references, yeast chromosome maps ...
E.coli database
Contains the same information as the previous site but for E.coli specifically.LINKS
Molecular biology today
Give links to those different subject : Genomes and Databases, Molecular Biology Journals, News Groups and Mail Lists, Institutes and Organizations, Commercial Sites...
Genetic linkage analysis
Bioinformatic and sequence analysis,forum in human genetics, linkage bibliography and publications.IMAGES
BULLFROGFILMS
Site where you can buy films about different subjects dealing with genetics
Not specific siteMISCELLANEOUS
Genetic discovery DNA paternity test
Commercial site selling DNA paternity tests (350 $)