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By dilating arteries, diltiazem reduces the pressure in the arteries into pris cardizem which the heart must pump blood, and, as result, the heart needs to work less and requires less oxygen. Angina Learn about the causes and symptoms of angina like pressure, heaviness, tightening, squeezing, and aching across the chest. Contraindications: Patients with known hypersensitivity to the drug. Such measures do not have any standardized meanings prescribed by GAAP, and are therefore unlikely to be comparable to similar measures presented by other companies. Diltiazem may also be used to treat irregular heartbeat or may be given after heart attack. Overdosage Any medication taken in excess can have serious consequences. If your symptoms do not improve or if they become worse, check with your doctor.