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In vitro preclinical studies have shown that buspirone has high affinity for serotonin 5-HT1A receptors. Subsequent dose adjustment of either drug should buspirone sem uma prescricao be based on clinical assessment. Haloperidol: In study in normal volunteers, concomitant administration of buspirone and haloperidol resulted in increased serum haloperidol concentrations. Comparison to Benzodiazepines Buspirone chemical structure and mechanism of action are completely unrelated to those of the benzodiazepines, but it purportedly has an efficacy comparable to that of diazepam Valium in treating GAD.
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